|Our research examines the mechanisms mediating contraction of the smooth muscle in the esophagus and Lower Esophageal Sphincter (LES). Disorders of esophageal motor function and LES competence, for instance gastroesophageal reflux disease, affect more than one in ten adults over 40 and one in four adults over 60 years of age. We investigate the inflammation-associated changes in the signaling mechanisms mediating esophageal contraction that occur with gastroesophageal reflux disease.||
KAREN HARNETT, PHD
Are you Karen Harnett? Click here to edit your research profile.