Our laboratory is interested in the developmental regulation of genes involved in the growh and function of the developing heart and placenta. In addition, we are studying the genetic architecture of preterm birth and preeclampsia. We are using a combination of bioinformatics, pathway analysis, genome wide associations and deep sequencing to identify causal variants.
Dr. Padbury received his BS in biology (Magna Cum Laude) from the University of California at Irvine and his MD degree from UCLA. His postgraduate training in pediatrics and neonatology was taken at UCSF, Harvard University (Boston Children's Hospital) and UCLA. He was recruited to Brown University from UCLA in 1995. His appointments at Brown are the OhZopfi Professor of Pediatrics and Perinatal Research, Pediatrician-In-Chief and Chief of Neonatal/Perinatal Medicine at the Women and Infants' Hospital and Associate-Chair for Research, Department of Pediatrics at the Hasbro Children's Hospital. He has a long-standing research interest in cardiovascular and placental developmental biology. Awards since coming to Brown University have included a program project grant in perinatal biology, establishment of T-32 supported perinatal biology training at WIH, a grant from HRSA for construction of the Kilguss Research Institute in the Jewelry District, two Center of Biomedical Research Excellence Awards (COBRE) for Perinatal Biology and a shared equipment grant for an Illumina high throughput DNA sequencing platform for the Genomics Core. He serves as an extramural reviewer for NIH, NSF, the American Heart Assn. and the March of Dimes. He is a member of the Child Health Advisory Committee of the Charles H. Hood Foundation, which awards research funds to new pediatric investigators in New England Universities. He is past Chair of the NIH Pregnancy and Neonatology Study Section (PN, 2001-07) and is currently on the NIH-NCRR Advisory Council. He is also a member of the editorial boards of the Journal of Pediatrics and the American Journal of Reproductive Immunology. He is a member of the Pathobiology, MCB and MPPB Interdepartmental Graduate Programs. He currently serves on 5 predoctoral committees and is thesis advisor to one PhD candidate in Pathobiology and an MPH candidate.
JAMES PADBURY, MD, UCLA (1973)
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COBRE for Perinatal Biology
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