Research in my laboratory focuses on the biochemical and biophysical underpinnings of DNA transactions essential for the maintenance of genomes and for controlling the flow of genetic information. Our approach combines biochemistry and biophysics with complementary structure determination methods (X-ray crystallography, small-angle X-ray scattering and electron microscopy) with the goal of elucidating the architecture, function, and regulation of protein and protein-nucleic acid complexes.

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Dr. Deaconescu received her undergraduate degree in chemical engineering from The Cooper Union for the Advancement of Science and Art in 2001, and then completed doctoral work in molecular biophysics at The Rockefeller University. Between 2006-2013, Dr. Deaconescu conducted postdoctoral research at Brandeis University and the HHMI Janelia Farm Research Campus in the laboratory of Dr. Nikolaus Grigorieff. Her work brought structural and mechanistic insight into the processes of transcription-coupled DNA repair and cytoskeleton regulation. She will join the Molecular Biology, Cell Biology and Biochemistry Department at Brown University in January, 2014. Dr. Deaconescu welcomes applications from undergraduates and postgraduates of diverse backgrounds and interests for work on a variety of exciting research projects.

Assistant Professor of Molecular Cell Biology and Biochemistry
Bio Med Molecular, Cellular Biology Biochemistry
Phone: 401-863-3215

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