Our research interests are aimed toward investigating and manipulating the noncovalent interactions that govern molecular recognition in biological systems. We are studying interactions between proteins and their ligands, between proteins and DNA, and the noncovalent interactions that dictate protein secondary and tertiary structure. These projects utilize traditional tools of organic chemistry such as synthesis and spectroscopic evaluation of molecular structure and conformation, and also employ a variety of more biological techniques such as electrophoresis, enzymology, and protein isolation and purification.
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