Rapid and accurate transitions between different gene expression programs are vitally important for cells to respond to changing metabolic requirements, developmental programs, and extracellular stimuli. The goal of our research program is to understand how a cell exploits the dynamic process of ubiquitin-mediated proteolysis to change patterns of gene expression and switch between alternate phenotypic states.
Jeff Laney received his B.S. degrees in Biochemistry and Biological Sciences from Florida State University in 1989. His graduate work in Molecular Biophysics and Biochemistry at Yale University (PhD, 1995) with Dr. Mark Biggin focused on transcriptional regulation during early Drosophila development. From 1997 to 2002, he was an American Cancer Society Postdoctoral Fellow with Dr. Mark Hochstrasser at the University of Chicago and Yale University, where he initiated his studies on regulated protein degradation and gene expression in the yeast Saccharomyces cerevisiae. He joined the Brown faculty in 2002.
JEFFREY LANEY, Ph.D.
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