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Hepatitis B (HBV) and C (HCV) viruses are the major etiological agents of primary hepatocellular carcinoma (HCC). Both viruses frequently cause chronic hepatitis leading to persistent liver injury, liver cirrhosis, and eventually HCC. The molecular mechanisms underlying the viral pathogenesis and carcinogenesis are poorly understood. Our current research projects focus on identification of host proteins required for the early stage of HBV life cycle, and viral-host interaction in HCV pathogenesis.
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M.D. Shanghai Medical University, Shanghai, China (1983). Ph.D.: Claud-Bernard University, Lyon, France (1992). Postdoctoral training: Massachusetts General Hospital Cancer Center, Harvard Medical School (1993-1999). Current employment: Associate Professor of Medicine, Liver Research Center, Rhode Island Hospital, Brown Medical School. Research interest: Hepatitis B and C virus: molecular virology and carcinogenesis.
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