SEAN DAVID

My research examines molecular determinants of smoking cessation combining formal skill sets in medicine, public health, pharmacogenetics/pharmacogenomics, and functional neuroimaging. I have conducted pharmacogenetics studies of nicotine replacement therapy and bupropion for smoking cessation, finding significant gene x treatment interactions for bupropion and identifying mediating pathways for bupropion smoking cessation efficacy. The overall goal is to translate this research to practice.

Overview  |  Research  |  Grants/Awards  |  Teaching  |  Publications

Biography

Dr. David is Director of Research in Family Medicine. His research spans the translational continuum from molecular genetics to health policy and is focused on smoking cessation. Recently published studies have identified genetic (pharmacogenetic and pharmacogenomic) influences on drug response to bupropion and nicotine replacement therapy for smoking cessation and have examined brain reward pathways using functional neuroimaging. He is actively translating these data into practice and policy through cost-effectiveness analyses, meta-analyses, and medical informatics working with a Trans-Atlantic transdisciplinary research team. He is also active in clinical practice and education.
Dr. David trained at the University of Washington, the Harvard School of Public Health, the University of Oxford where he was mentored by Sir Richard Doll, was Chief Resident at Dartmouth-Hitchcock Medical Center, and a Robert Wood Johnson Foundation Generalist Physician Faculty Scholar. He has worked as a collaborator and protégé of former Surgeon General C. Everett Koop on numerous projects translating nicotine dependence research into tobacco control policy. He is also Director of the Primary Care Genetics Laboratory & Translational Research Center and C. Everett Koop Health Policy Fellowship.

Curricum Vitae

Download Sean David's Curriculum Vitae in PDF Format

SEAN DAVID, MD, SM, DPhil
Adjunct Assistant Professor of Family Medicine
Bio Med Family Medicine
Phone: +1 401 729 2071
Phone 2: +1 401 265 2275
E-mail: Sean_David@Brown.EDU

Sean David's Brown Research URL:
http://research.brown.edu/myresearch/Sean_David

On The Web:
Primary Care Genetics Laboratory and Translational Research Center

Brown collaborators:

Collaborators at other institutions:
Marcus Munafo', University of Bristol
Elaine Johnstone, University of Oxford
Paul Matthews, University of Oxford
Caryn Lerman, University of Pennsylvania
Nancy Rigotti, Harvard University
A. Eden Evins, Harvard University
Elyse Park, Harvard University
Gary Swan, SRI International
Andrew Bergen, SRI International
Christina Lessov-Schlaggar, Washington University, St. Louis
Peter Shields, Georgetown University
George Uhl, NIDA Intramural Research Program, Johns Hopkins University
Jed Rose, Duke University

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