DEBORAH CIOMBOR

Dr. Deborah McK. Ciombor's research focuses on cell-based tissue engineering to create a transplantable biocomposite cartilage replacement that may be able to restore function lost to trauma or disease. A stem cell population has been identified in joint lining tissues (synovium) that can be differentiated into cartilage cells by exposure to specific sequences of growth factors.

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Biography

Dr. Deborah McK. Ciombor is Associate Professor of Orthopaedics (Research) and Molecular Pharmacology, Physiology and Biotechnology (Research). She is the Associate Director of the Center for Restorative and Regenerative Medicine, Providence VA Medical Center/Brown University.

Dr. Ciombor completed her BS in Biology at Brown University and PhD in Biochemistry and Biophysics at the University of Rhode Island in 1992. Dr. Ciombor began her research career studying the effects of physical stimuli on connective tissue, particularly electomagnetic fields. The work centered on the modulation of chondrocyte differentiation. She is currently examining the modulation of growth factor effects and the transduction of the physical signal from recognition to gene regulation. Recent work in the laboratory is focused on tissue engineering and the application of developmental biology to the production of cartilage biocomposites. She has been the co-director of the Duffy Cell Biology Laboratory at the Department of Orthopaedics at Rhode Island Hospital and Alpert Brown Medical School since 2001. The laboratory has been continuously funded through a combination of government, corporate and foundation grants.

DEBORAH CIOMBOR, PhD
Associate Professor of Orthopaedics (Research)
Orthopaedics; Molecular Pharmacolgy, Physiology & Biotechnology
Phone: +1 401 444 5331
Phone 2: +1 401 444 4485
E-mail: Deborah_Ciombor@Brown.EDU

Deborah Ciombor's Brown Research URL:
http://research.brown.edu/myresearch/Deborah_Ciombor

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