Our laboratory is focused on studying the pathogenesis of the human polyomaviruses, JC Virus (JCV) and BK Virus (BKV). Reactivation of JCV under conditions of immunosuppression leads to the fatal demyelinating disease in humans known as Progressive Multifocal Leukoencephalopathy (PML). Approximately 5% of patients with AIDS will develop PML and the majority succumb within two years of diagnosis. Reactivation of BKV in kidney transplant recipients has emerged as a major problem in the last decade and is responsible for nearly half of all kidney transplant failures. The major focus of the lab is studying early events that mediate infection of cells by these viruses.
B.S. 1986. Microbiology, University of Massachusetts, Amherst
WALTER ATWOOD, PHD
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Antipsychotic Drugs Stop Fatal Viral Infection in Brain Cells
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