Successful wound healing requires the coordinated activities of the multiple cell types that constitute the inflammatory and reparative response to tissue injury. The definition of the growth factors, cytokines, matrix components, and other products present in the wound that modulate wound healing-cell functions will allow a better understanding of the process of repair and promises clinical applications that will allow active therapeutic intervention. The development of these applications will require a better characterization of the phenotype and biology of inflammatory cells, most specifically as it relates to modulation by the wound environment.
Dr. Jorge E. Albina is Professor of Surgery and Director of Surgical Research at Rhode Island Hospital/Alpert Medical School of Brown University, and Director of Nutritional Support Services, Department of Surgery, Rhode Island Hospital.
JORGE E. ALBINA, M.D., Universidad Nacional La Plata, Argentina
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