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The goal of the Darling lab is to understand the relationship between the biological function of cells and tissues and their micro/nano-scale mechanical properties. We investigate these characteristics via atomic force microscopy, a technique that allows high resolution imaging and force measurements. Recent findings suggest that cells exhibit distinct mechanical biomarkers, which could help identify specific cell types within heterogeneous populations (i.e. metastatic cancer cells, stem cells).
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Eric Darling is an Assistant Professor of Medical Science in the Department of Molecular Pharmacology, Physiology, and Biotechnology with courtesy appointments in the Department of Orthopaedics and the School of Engineering. He received a B.S. in Engineering from Harvey Mudd College, a Ph.D. in Bioengineering from Rice University, and post-doctoral training at Duke University. As a member of the Center for Biomedical Engineering, the goal of Professor Darling's research is to understand the relationship between the biological function of cells and tissues and their micro/nano-scale mechanical properties, with special focus on stem cells. Professor Darling's long-term objective is to use quantitative assessment of the mechanical and biological characteristics of single cells to improve tissue regeneration and cell-based therapies.
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 ERIC DARLING, Ph.D., Rice University http://research.brown.edu/myresearch/Eric_Darling On The Web: Darling Lab webpage Force scanning: quick maps and measurements of living cells Brown collaborators:
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