EDWARD STOPA

Alzheimer's disease (AD) is generally regarded as a degenerative disease, but many normal physiological processes are increased in AD patients. My research deals with proteins involved in three major physiological processes in the brain: cell growth and differentiation; maintaining the environment between neurons (the extra-cellular matrix); and the inflammatory response. The question is whether these proteins and physiological processes play a critical role in initiating the disease or whether they are increased as a result of the disease.

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Biography

Dr. Stopa began his academic appointment at Brown University School of Medicine in 1993 and is presently a Professor (Research Scholar Track) in the Department of Pathology. Dr. Stopa is also the current Director of the Neuropathology Division at Rhode Island Hospital, one of Brown's seven affiliated hospitals. In addition, Professor Stopa oversees the Brown Brain Bank, which provides human tissue for purposes of basic and translational research for the Department of Neuroscience.

Before arriving at Brown, Dr. Stopa had a distinguished career as an Assistant Professor of Pathology at Tufts University School of Medicine, and as an Associate Professor of Pathology at the State University of New York. Since 1985, he has continued to serve as a research affiliate in Neuropathology for Harvard Medical School's McLean Hospital Human Brain Tissue Research Center. He was the recipient of a Physician Scientist Award from the National Institute on Aging, and trained in the laboratories of Dr Joan King and Dr Seymour Reichlin . He has over 80 articles to his credit in such prestigious publications as Science, Proceedings of the National Academy of Sciences, Brain Research, Endocrinology, New England Journal of Medicine and Annals of Neurology.

While affiliated with Brown, Dr. Stopa has made great strides in the understanding and treatment of aging and Alzheimer's disease through close collaborations with both basic and clinical neuroscientists. He has also been interested in neuroendocrinology, and has contributed extensively to our knowledge of the hypothalamic mechanisms that are responsible for human reproduction and circadian rhythmicity.

Curricum Vitae

Download Edward Stopa's Curriculum Vitae in PDF Format

EDWARD STOPA, MD
Professor
Pathology & Laboratory Medicine
Phone: +1 401 444 5057
E-mail: Edward_Stopa@Brown.EDU

Edward Stopa's Brown Research URL:
http://research.brown.edu/myresearch/Edward_Stopa

Brown collaborators:

Collaborators at other institutions:
Andrew Baird, Ph.D.
David Harper, Ph.D.
Andrew Satlin, M.D.

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