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We study the cellular mechanisms that control the precise architectural features of calcium ion channels in neurons. Why? Because these mechanisms are key to understanding how voltage-gated calcium ion channels control such a vast and disparate array of neuronal functions. Alternative pre-mRNA splicing fine tunes calcium ion channel structure in specific neurons for optimal performance. Our work addresses basic mechanisms that control calcium channel function in normal as well as in disease states, including chronic pain.
Overview | Research | Grants/Awards | Teaching | Publications
I graduated with a PhD in Pharmacology from University College London in 1986. My journey into the world of calcium ion channels started when I joined Richard Tsien as a postdoc at Yale University and subsequently Stanford University. In 1992 I joined the Department of Neuroscience where I work closely with undergraduate and graduate students, as well as postdoctoral trainees. I direct the Neuroscience Graduate Program.
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 DIANE LIPSCOMBE, Ph.D., University College, London http://research.brown.edu/myresearch/Diane_Lipscombe On The Web: Lipscombe Lab Brown collaborators:Are you Diane Lipscombe? Click here to edit your research profile. |
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