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Professor of Clinical Neuroscience (Neurosurgery) Conrad Johanson investigates the transport and permeability roles of the blood-Cerebrospinal Fluid (CSF) interface (choroid plexus) and blood-brain barrier (cerebral capillaries) in regulating the neuronal fluid environment. His research involves models of ischemia, hydrocephalus, and aging to clarify how CSF and brain interstitial fluid homeostatic mechanisms are altered in Alzheimer's disease. The goal is to identify pharmacological strategies for preventing or repairing damage to 'barrier cells' that defend the integrity of brain fluids.
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